Study Reports Increase in HIV-infected Patients with Bone Marrow Cancer in KZN

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Senior Registrar and KwaZulu-Natal (KZN) Academic Complex Haematopathologist at Inkosi Albert Luthuli Central Hospital’s (IALCH) Haematology Department, Dr Lungisile Chili, beamed with pride and joy when her name was read out before graduating with her Master of Medicine degree in Haematology.

Her passion for innovation in medicine stems from her suffering from chronic allergic rhinitis as a child, which upset her whole family. She is satisfied with her latest accomplishment, and optimistic about her department’s contribution to health research and policy-making. ‘I hope to conduct more impactful research that ultimately contributes to improving the quality of life in developing countries,’ said Chili. 

Her dissertation, profile and Outcome of Multiple Myeloma With and Without HIV Treated at a Tertiary Hospital in KwaZulu-Natal, South Africa is a novel study. It was co-supervised by Professor Irene Mackraj of the School of Laboratory and Medical Sciences and Dr Nadine Rapiti who heads the Haematology KZN Academic Complex at IALCH. 

The study confirmed an increase in the number of HIV-infected patients newly-diagnosed with a type of bone marrow cancer known as multiple myeloma (MM) in KwaZulu-Natal. The province’s patient profile differed from that of other regions in that it points to female predominance, but was similar in advanced-stage presentation and bone fracture predominance. ‘Statistically significant differences between the HIV-negative patients and people living with HIV were observed in terms of age distribution and the mutational landscape. Further studies are required in this area,’ Chili said. 

Like her fellow scientists and researchers, Chili’s study was challenged by the outbreak of COVID-19 but her desire to improve patient care through meaningful research encouraged her to persevere.

‘Heartfelt congratulations to Dr Chili who has demonstrated exceptional aptitude for research and is well-positioned for continued achievement in pursuit of a doctoral degree. She is a role model for young researchers in her field,’ said Mackraj. 

‘Congratulations Dr Chili on your accomplishment! This marks the end of a challenging journey in learning, and the beginning of your career as a research leader, teacher and mentor in haematology. Your research highlighted the long time to diagnosis, and the need for myeloma education and supportive care, which you’ve already initiated. Invaluable work, and patients are already reaping the rewards,’ Rapiti said. 

Chili said she enjoys spending time with her daughter, singing, listening to music, dancing and the arts. She is keen to assist and support other keen professionals. ‘I enjoy innovative and meaningful engagement.’ 

Words: Lunga Memela

Photograph: Sethu Dlamini