Genital Inflammation Reduces Efficacy of Tenofovir Gel: Study Sheds New Light on Why Topical PrEP Effectiveness Varies in Women
Why do some women get HIV infection, even though they are using tenofovir gel for prophylaxis? A new study by scientists at the Centre for the AIDS Programme of Research in South Africa (CAPRISA), published in Nature Medicine recently, shows that genital inflammation significantly reduces the effectiveness of tenofovir gel in preventing HIV infection in women.